Faculty - Angela Wilks
Selected Publications
Suntara Eakununkul, Arundhati Ghosh, Gudrun S. Lukat Rodgers, Suganya Sumithran, Kenton R.Rodgers, John S. Dawson, and Angela Wilks, “Characterization of the Periplasmic Heme-binding Protein ShuT from the Heme Uptake System of Shigella dysenteriae.” Biochemistry (2005) 44, 13179-91.
Rahul Deshmukh, Yuhong Zeng, Lena M. Furci, Hong-wei Huang, Bailey N. Morgan, Suzanne Sander, Aileen Y. Alontaga, Richard A. Bunce, Pierre Moënne-Loccoz, Mario Rivera, and Angela Wilks. “Heme oxidation in a chimeric protein of the α-selective Neisseriae meningitidis Heme Oxygenase with the distal helix of the δ-selective Pseudomonas aeruginosa.” Biochemistry (2005) 44, 13713-23.
Ila B. Lansky, Gudrun S. Lukat-Rodgers, Darci Block, Kenton R. Rodgers, Melanie Ratliff, and Angela Wilks, “The cytoplasmic heme-binding protein (PhuS) from the heme uptake system of Pseudomonas aeruginosa is an intracellular heme-trafficking protein to the delta-regioselective heme oxygenase” J. Biol. Chem. (2006) 281, 13652-62.
Mehul N. Bhakta and Angela Wilks “The Mechanism of Heme Transfer from the Cytoplasmic Heme Binding Protein PhuS to the -regioselective Heme Oxygenase of Pseudomonas aeruginosa.” Biochemistry (2006) 45, 11642-11649.
Ajinder P. Kaur and Angela Wilks “Heme inhibits the DNA-binding properties of the cytopalsmic heme-binding protein ShuS of Shigella dysenteriae.” Biochemistry (2007) 46, 2994-3000.
Kimberly A. Burkhard and Angela Wilks “Characterization of the outer-Membrane Receptor ShuA from the Heme Uptake System of Shigella dysenteriae: Substrate Specificity and Identification of the Heme-Protein Ligands.” J. Biol. Chem. (2007) 282, 15126-15136.
Lena M. Furci, Pedro Lopes, Suntara Eakanunkul, Shijun Zhong, Alexander D. MacKerell Jr., and Angela Wilks “Inhibition of the Bacterial Heme Oxygenases from Pseudomonas aeruginosa (pa-HO) and Neisserria meningitidis (nm-HO): A Novel Antimicrobial Target? (2007) J. Med. Chem. 50, 3804-13.
Kellie Hom, Rahul Deshmukh, Lena M. Furci, and Angela Wilks, “NMR assignments of cd-HO, a 24 kDa heme oxygenase from Corynebacterium diphtheriae.” (2007) Biomol NMR Assign 1, 55-56.
Mehul N. Bhakta and Angela Wilks, “Catalytic Turnover Dependent Modification of the Pseudomonas aeruginosa Heme Oxygenase (pa-HO) by 5,6-O-Isopropyledine-2-O-Allyl-Ascorbic Acid.” J. Inorg. Biochem. (2008) 102, 251-259.
Darci Block, Gudrun S. Lukat-Rodgers, Kenton R. Rodgers, Angela Wilks, Mehul N. Bhakta, Ila B. Lansky. Identification of Two Heme-binding Sites in the Cytoplasmic Heme-trafficking Protein PhuS from Pseudomonas aeruginosa and Their Relevance to Function. (2007) Biochemistry 46, 14391-14402.
Winny H. Wo, Huiying Li, Suntara Eakanunkul, Yong Tong, Angela Wilks, Mailin Guo, and Thomas L. Poulos. Holo- and Apo- Structures of Periplasmic Heme Binding Proteins. J. Biol. Chem. (2007) 282, 35976-35802.
Kimberly A. Burkhard and Angela Wilks, Functional Characterization of the Shigella dysenteriae ABC-transporter, ShuUV. Biochemistry, (2008) 47, 7977-7979.