Computer-Aided Drug Design
Drug Design Projects in Progress
| Collaborator | Institution | Target/Status |
| Archontis & Spiros | Univ. of Cyprus | glycogen phosphorylase, lead optimization in progress |
| Coop | UMB, Pharmacy | Opioids/Analgesics, lead optimization in progress, NIH R01; funded |
| DiGate | UMB, Pharmacy | Topoisomersase, active cmp identified NIH R21; submitted |
| Hayashi | UMB, Pharmacy | p56lck kinase, active cmpds identified, patent pend. NIH R01; funded |
| Neamati | USC, Pharmacy | HIV Integrase, active cmpd identified, publications, NIH R01; submitted |
| Oikonomakos | Inst. Organic & Pharmaceutical Chem. Nat. Hellenic Res. Fd. Greece | glycogen phosphorylase/phosphorylase kinase, Greek Secretariat for Research and Technology, International S & T Cooperation Directorate, Grant; submitted |
| Passaniti | UMB, Medicine | Runt Domain/angiogenesis, active cmpds identified, NIH R21; funded |
| Serrero | UMB, Pharmacy | PCDGF/breast cancer, active cmpds identified, DoD Concept Award; Funded |
| Shapiro | UMB, Pharmacy | ERK kinase, active cmpds identified, NIH R21; funded |
| Srivistava | UMB, Pharmacy | Death Receptor/Apoptosis, CADD screen complete, DoD Idea Award; Funded |
| Sussman | UMB, Pharmacy | b-Catenin/colon Cancer, active cmpds identified, NIH R21; funded |
| Weber | UMB, Medicine | S100b - P53 Interactions, Active cmpds identified, ACS funded, NIH R01; submitted |
| Zhang | Univ. of Texas, Southwest Med. Center | Adenosyltransferase, Active compounds identified. NIH R01 submitted. |